Besides being the setting of Michael Ondaatje's In the Skin of a Lion, the Prince Edward Viaduct has appeared in movies, music videos, and other works of literature. It has also been mentioned in several songs, including "War on Drugs" by the Barenaked Ladies, "Anything Could Happen" by Bruce Cockburn, and "National Hum" by The Constantines, and was even part of a suicide storyline on Degrassi Junior High.